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STEMCELL Technologies GSA 10
Hedgehog pathway activator; Activates Smoothened (SMO)
Brand: STEMCELL Technologies 73174
Additional Details : Weight : 0.05000kg
Description
- GSA 10 is an agonist of Smoothened (SMO), a cell surface receptor and mediator of the hedgehog signaling pathway
- It is a quinolinecarboxamide derivative that binds in a distinct binding pocket from cyclopamine
- GSA10 is active at an EC50 of 1.2 μM in an alkaline phosphatase-based mouse mesenchymal cell line (C3H10T1/2) differentiation assay (Gorojankina et al.)
- Promotes differentiation of multipotent mesenchymal progenitor cells into osteoblasts (Gorojankina et al.)
Specifications
300833-95-8 | |
50 mg | |
C26H30N2O5 | |
≥95% |