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STEMCELL Technologies GSA 10

Hedgehog pathway activator; Activates Smoothened (SMO)

POA - 13464.90 SEK

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Product Code	Brand	Quantity	Price	Quantity & Availability
Product Code	Brand	Quantity	Price	Quantity & Availability
17140182 View Documents Promotion Details missing translation for 'viewProductCertificates'	STEMCELL Technologies 73172	10 mg	POA 10mg View alternative products Save Up to »	N/A	Please sign in to purchase this item. Need a web account? Register with us today!
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17150182 View Documents Promotion Details missing translation for 'viewProductCertificates'	STEMCELL Technologies 73174	50 mg	13464.90 SEK 50mg View alternative products Save Up to »	Estimated Shipment: 16-08-2024 Log in to see stock.	Please sign in to purchase this item. Need a web account? Register with us today!

Description

GSA 10 is an agonist of Smoothened (SMO), a cell surface receptor and mediator of the hedgehog signaling pathway
It is a quinolinecarboxamide derivative that binds in a distinct binding pocket from cyclopamine
GSA10 is active at an EC₅₀ of 1.2 μM in an alkaline phosphatase-based mouse mesenchymal cell line (C3H10T1/2) differentiation assay (Gorojankina et al.)
Promotes differentiation of multipotent mesenchymal progenitor cells into osteoblasts (Gorojankina et al.)

Specifications

Description