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HLA DQ Antibody (SPV-L3), Novus Biologicals™

Mouse Monoclonal Antibody has been used in 3 publications

2655.00 SEK - 4640.00 SEK

Specifications

Antigen HLA DQ
Clone SPV-L3
Concentration 0.2 mg/mL
Dilution Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Frozen 0.5 - 1.0 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml
Applications Flow Cytometry, Immunohistochemistry (Frozen), Immunofluorescence
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
18179208
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Bio-Techne
NBP2-45041-0.02MG
0.02 mg
2655.00 SEK
0.02mg
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18022346
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Novus Biologicals
NBP2-45041-0.1MG
0.1 mg
4640.00 SEK
0.10mg
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Description

Description

Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

HLA DQ Monoclonal specifically detects HLA DQ in Human, Porcine samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunofluorescence.
Specifications

Specifications

HLA DQ
0.2 mg/mL
Flow Cytometry, Immunohistochemistry (Frozen), Immunofluorescence
Unconjugated
Mouse
Adaptive Immunity, Asthma, Immunology
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
3117
T4-positive CTL clone HG-38
Primary
Store at 4C.
60 kDa
SPV-L3
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Frozen 0.5 - 1.0 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml
Monoclonal
Purified
RUO
Human, Porcine
CD, CELIAC1DQ alpha 1 chain, DC-1 alpha chain, DQ-A1, FLJ27088, FLJ27328, GSE, HLA class II histocompatibility antigen, DQ(W3) alpha chain, HLA-DCA, HLA-DQA, leucocyte antigen DQA1, leukocyte antigen alpha chain, major histocompatibility complex, class II, DQ alpha 1, MGC149527, MHC class II antigen, MHC class II DQA1, MHC class II HLA-D alpha glycoprotein, MHC class II HLA-DQ-alpha-1, MHC class II surface glycoprotein, MHC HLA-DQ alpha
HLA-DQ
IgG2a κ
Protein A or G purified
Recognizes a DQ antigen, which is a dimer of 60kDa. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. This MAb strongly blocks cytotoxicity activity of T4-positive cytotoxic T cell clones.
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