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Tocris Bioscience™ I-BET 762

Potent and high affinity BET bromodomain inhibitor; anti-inflammatory; orally bioavailable.

Brand: Tocris Bioscience™ 6521/25

3974.26 SEK valid until 2024-12-16
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Product Code. 18094322

4905.00 SEK / 25mg

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Description

I-BET 762 is a potent and high affinity BET bromodomain inhibitor (IC50 = 32.5 - 42.5 nM; Kd = 50.5 - 61.3 nM). Inhibits myeloma cell proliferation. Attenuates transcription of oncogenic MYC and suppresses key inflammatory genes. Exhibits efficacy in a range of oncology and immunoinflammatory models. Displays antiproliferative effect in vitro and in vivo. Orally bioavailable.

Specifications

Chemical Name or Material	(4S)-6-(4-Chlorophenyl)-N-ethyl-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-4-acetamide
Quantity	25 mg
Molecular Formula	C₂₂H₂₂ClN₅O₂

CAS	1260907-17-2
Target	Bromodomain Inhibitors
Purity	0.98

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Tocris Bioscience™ I-BET 762

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