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Tocris Bioscience™ I-BET 762
Potent and high affinity BET bromodomain inhibitor; anti-inflammatory; orally bioavailable.
1435.00 SEK - 4905.00 SEK
Specifications
| Chemical Name or Material | (4S)-6-(4-Chlorophenyl)-N-ethyl-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-4-acetamide |
|---|---|
| CAS | 1260907-17-2 |
| Target | Bromodomain Inhibitors |
| Molecular Formula | C22H22ClN5O2 |
| Purity | 0.98 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18094322
|
Tocris Bioscience™
6521/25 |
25 mg |
4905.00 SEK
25mg |
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|
18054232
|
Tocris Bioscience™
6521/5 |
5 mg |
1435.00 SEK
5mg |
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Description
I-BET 762 is a potent and high affinity BET bromodomain inhibitor (IC50 = 32.5 - 42.5 nM; Kd = 50.5 - 61.3 nM). Inhibits myeloma cell proliferation. Attenuates transcription of oncogenic MYC and suppresses key inflammatory genes. Exhibits efficacy in a range of oncology and immunoinflammatory models. Displays antiproliferative effect in vitro and in vivo. Orally bioavailable.Specifications
| (4S)-6-(4-Chlorophenyl)-N-ethyl-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-4-acetamide | |
| Bromodomain Inhibitors | |
| 0.98 |
| 1260907-17-2 | |
| C22H22ClN5O2 |
Safety and Handling
Recommended Storage : Store at -20°C