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ICA 069673
KV7.2/KV7.3 channel opener
Brand: Tocris Bioscience 4305/25
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Description
ICA 069673 is a selective KV7.2/KV7.3 (KCNQ2/3) channel opener (EC50 = 0.69 μM). Exhibits 20-fold selectivity for KV7.2/KV7.3 over KV7.3/KV7.5, with no measurable activity over a panel of cardiac ion channels. Hyperpolarizes resting membrane potential and inhibits spontaneous action potentials in guinea pig detrusor muscle (DSM) isolated cells. Orally active in animal models of epilepsy.
Specifications
| N-(2-Chloro-5-pyrimidinyl)-3,4-difluorobenzamide | |
| >99% | |
| C11H6ClF2N3O |
| 582323-16-8 | |
| 25 mg | |
| Observed MW: 269.63 |
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Product Title
ICA 069673 > 25mg
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