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Lifitegrast, MedChemExpress

MedChemExpress Lifitegrast (SAR 1118) is a potent integrin antagonist. Lifitegrast blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast can be used for researching dry eye disease.

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1058.12 SEK - 4668.18 SEK

Specifications

Chemical Name or Material Lifitegrast
CAS 1025967-78-5
Color Off-White
Purity Grade Notes Research
Molecular Formula C29H24Cl2N2O7S
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Description

Description

Lifitegrast (SAR 1118) is a potent integrin antagonist. Lifitegrast blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast can be used for researching dry eye disease.
Specifications

Specifications

Lifitegrast
Off-White
C29H24Cl2N2O7S
DMSO : ≥ 29 mg/mL (47.12 mM)
615.48
99.09%
Solid
1025967-78-5
Research
SAR 1118 SHP-606
O=C(O)[C@H](CC1=CC=CC(S(=O)(C)=O)=C1)NC(C2=C(Cl)C3=C(CN(C(C4=CC=C5C=COC5=C4)=O)CC3)C=C2Cl)=O
615.48
Research
COVID-19-immunoregulation
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Safety and Handling

Safety and Handling

missing translation for 'shelfLife' : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month

Recommended Storage : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month

SDS
Documents

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Product Certifications

Research purposes only

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Lifitegrast, MedChemExpress

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