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Lifitegrast, MedChemExpress
MedChemExpress Lifitegrast (SAR 1118) is a potent integrin antagonist. Lifitegrast blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast can be used for researching dry eye disease.

1058.12 SEK - 4668.18 SEK
Specifications
Chemical Name or Material | Lifitegrast |
---|---|
CAS | 1025967-78-5 |
Color | Off-White |
Purity Grade Notes | Research |
Molecular Formula | C29H24Cl2N2O7S |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16497738
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Medchem Express
HY-19344 |
10 mg |
1058.12 SEK
10mg |
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16433717
![]() |
Medchem Express
HY-19344 |
50 mg |
2894.28 SEK
50mg |
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16407606
![]() |
Medchem Express
HY-19344 |
100 mg |
4668.18 SEK
100mg |
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Description
Lifitegrast (SAR 1118) is a potent integrin antagonist. Lifitegrast blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast can be used for researching dry eye disease.Specifications
Lifitegrast | |
Off-White | |
C29H24Cl2N2O7S | |
DMSO : ≥ 29 mg/mL (47.12 mM) | |
615.48 | |
99.09% | |
Solid |
1025967-78-5 | |
Research | |
SAR 1118 SHP-606 | |
O=C(O)[C@H](CC1=CC=CC(S(=O)(C)=O)=C1)NC(C2=C(Cl)C3=C(CN(C(C4=CC=C5C=COC5=C4)=O)CC3)C=C2Cl)=O | |
615.48 | |
Research | |
COVID-19-immunoregulation |
Safety and Handling
missing translation for 'shelfLife' : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Recommended Storage : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Research purposes only
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