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Lifitegrast, MedChemExpress

MedChemExpress Lifitegrast (SAR 1118) is a potent integrin antagonist. Lifitegrast blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast can be used for researching dry eye disease.

Brand:  Medchem Express HY-19344

Encompass_Preferred

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Product Code. 16433717

  • 2894.28 SEK / 50mg

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Description

Description

Lifitegrast (SAR 1118) is a potent integrin antagonist. Lifitegrast blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast can be used for researching dry eye disease.
Specifications

Specifications

Lifitegrast
Off-White
C29H24Cl2N2O7S
SAR 1118 SHP-606
O=C(O)[C@H](CC1=CC=CC(S(=O)(C)=O)=C1)NC(C2=C(Cl)C3=C(CN(C(C4=CC=C5C=COC5=C4)=O)CC3)C=C2Cl)=O
615.48
Research
COVID-19-immunoregulation
1025967-78-5
Research
50 mg
DMSO : ≥ 29 mg/mL (47.12 mM)
615.48
99.09%
Solid
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Lifitegrast, MedChemExpress

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Research purposes only