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Eurofins DiscoverX PASK Protein, Active
Active, N-terminal 6His-tagged, recombinant, human PASK, for use in Kinase Assays
6053.08 SEK - 46199.43 SEK
Specifications
| Formulation | mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. |
|---|---|
| Molecular Weight (g/mol) | 41.5 kDa |
| Species | Human |
| Recombinant | Recombinant |
| Protein Tag | N-terminal 6His |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
17380584
|
Eurofins DiscoverX
14-701 |
10 μg |
6053.08 SEK
10µg |
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|
17390584
|
Eurofins DiscoverX
14-701M |
250 μg |
46199.43 SEK
250µg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Serine/threonine-protein kinase involved in energy homeostasis and protein translation. Phosphorylates EEF1A1, GYS1, PDX1 and RPS6. Probably plays a role under changing environmental conditions (oxygen, glucose, nutrition), rather than under standard conditions. Acts as a sensor involved in energy homeostasis: regulates glycogen synthase synthesis by mediating phosphorylation of GYS1, leading to GYS1 inactivation. May be involved in glucose-stimulated insulin production in pancreas and regulation of glucagon secretion by glucose in alpha cells; however such data require additional evidences. May play a role in regulation of protein translation by phosphorylating EEF1A1, leading to increase translation efficiency. May also participate in respiratory regulation.
GenBank NM_015148
Specifications
| mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. | |
| Human | |
| N-terminal 6His | |
| Truncated | |
| PASK, active |
| 41.5 kDa | |
| Recombinant | |
| Recombinant enzyme expressed in Sf21 insect cells | |
| ≥36% |
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