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Eurofins DiscoverX Plk1 Protein, Active
Active, N-terminal 6His tagged, recombinant, human Plk1, for use in Kinase Assays.
5796.39 SEK - 44240.30 SEK
Specifications
| Formulation | mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. |
|---|---|
| Molecular Weight (g/mol) | 69.3 kDa |
| Species | Human |
| Recombinant | Recombinant |
| Protein Tag | N-terminal 6His |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
17300704
|
Eurofins DiscoverX
14-777 |
10 μg |
5796.39 SEK
10µg |
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|
17310704
|
Eurofins DiscoverX
14-777M |
250 μg |
44240.30 SEK
250µg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Polo-like kinases (PLKs) are a family of serine/threonine kinases related to the polo gene product of Drosophila melanogaster, originally identified from a mitotic mutant that displayed abnormal spindle poles. PLKs play essential roles in several stages of mitosis and cytokinesis with a dynamic pattern of localization to centrosomes, kinetochores and central spindle structures during the cell cycle. PLK1 has been shown to be overexpressed in many human tumours, such as non-small cell lung cancer, squamous cell carcinomas of the head and neck, melanomas, oropharyngeal carcinomas, and ovarian and endometrial carcinomas.
GenBank NM_005030
Specifications
| mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. | |
| Human | |
| N-terminal 6His | |
| Full-length | |
| Plk1, active |
| 69.3 kDa | |
| Recombinant | |
| Recombinant protein expressed in Sf21 insect cells | |
| ≥72% |