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Tocris Bioscience™ SR 9238

Potent and selective LXR inverse agonist

Brand:  Tocris Bioscience™ 5854/50

7084.05 SEK valid until 2024-12-16
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Product Code. 18750848

  • 8950.00 SEK / 50mg

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Description

Description

SR 9238 is a potent and selective LXR inverse agonist (IC50 values are 43 and 214 nM for LXRβ and LXRα, respectively). Selectively inhibits liver LXR over peripheral LXR. Exhibits selectivity for LXR over a panel of 20 other nuclear receptors, including FXR. Reduces hepatic steatosis in obese mice.
Specifications

Specifications

Ethyl 5-[[[[3′-(Methylsulfonyl)[1,1′-biphenyl]-4-yl]methyl][(2,4,6-trimethylphenyl)sulfonyl]amino]methyl]-2-furancarboxylate
50 mg
C31H33NO7S2
>98%
1416153-62-2
LXR-like Receptor Antagonists
595.73
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