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Tyrosinase Ab-1 Mouse Monoclonal Antibody, Epredia™
Provide accurate, reproducible results with the Epredia™ Tyrosinase Ab-1, Mouse Monoclonal Antibody.
1275.00 SEK - 7825.00 SEK
Specifications
| Antigen | Tyrosinase Ab-1 |
|---|---|
| Clone | T311 |
| Applications | Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot |
| Classification | Monoclonal |
| Host Species | Mouse |
| Product Code | Brand | Form | Conjugate | Quantity | Price | Quantity & Availability | |||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Form | Conjugate | Quantity | Price | Quantity & Availability | |||
|
12612337
|
Epredia
MS-800-B0 |
Concentrated | Biotin | 100 μL | N/A | ||||
|
12622337
|
Epredia
MS-800-B1 |
Concentrated | Biotin | 500 μL |
5995.00 SEK
500µL |
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|
12602337
|
Epredia
MS-800-B |
Concentrated | Biotin | 1 mL | N/A | ||||
|
12642337
|
Epredia
MS-800-P0 |
Concentrated | Unconjugated | 100 μL | N/A | ||||
|
12662337
|
Epredia
MS-800-P1ABX |
Concentrated | Unconjugated | 100 μL | N/A | ||||
|
12672337
|
Epredia
MS-800-PABX |
Concentrated | Unconjugated | 200 μL | N/A | ||||
|
12652337
|
Epredia
MS-800-P1 |
Concentrated | Unconjugated | 500 μL | N/A | ||||
|
12632337
|
Epredia
MS-800-P |
Concentrated | Unconjugated | 1 mL |
7825.00 SEK
1mL |
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|
12602347
|
Epredia
MS-800-R7 |
Prediluted | Unconjugated | 7 mL | N/A | ||||
|
12612347
|
Epredia
MS-800-RQ |
Ready-to-Use | Unconjugated | 12 mL |
4335.00 SEK
12mL |
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Description
Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients.Host Species: Mouse
Clone: T311
Isotype: IgG2a
Species Reactivity: Human, Dog and Cat. Weakly cross-reacts with Mouse. Others not known.
Epitope: aa 1-433
Immunogen: Recombinant tyrosinase protein
Molecular Weight: 70-80kDa
Positive Control: Melanoma cell lines and Melanoma
Cellular Localization: Cytoplasmic Ab-1 shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Staining of melanomas with Ab-1 showed tyrosinase in melanotic as well as amelanotic variants. Ab-1 is a useful marker for melanocytes and melanomas. Occasionally a minor band at 55kDa is also detected in Western Blotting
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunofluorescence
- Immunocytology
Specifications
| Tyrosinase Ab-1 | |
| Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
| Mouse | |
| Cancer and Tumor Biology | |
| Primary |
| T311 | |
| Monoclonal | |
| IVD | |
| Recombinant tyrosinase protein |
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