missing translation for 'onlineSavingsMsg'
Learn More

STEMCELL Technologies Anacardic Acid

Epigenetic modifier; Inhibits histone acetyltransferase (HAT)

View More Specs

Products 2

Product Code	Brand	Quantity	Price	Quantity & Availability
Product Code	Brand	Quantity	Price	Quantity & Availability
17170182 View Documents Promotion Details missing translation for 'viewProductCertificates'	STEMCELL Technologies 73192	1 mg	N/A View alternative products Save Up to »	N/A

17180182 View Documents Promotion Details missing translation for 'viewProductCertificates'	STEMCELL Technologies 73194	5 mg	N/A View alternative products Save Up to »	N/A

Description

Anacardic Acid is a 6-alkyl salicyclic acid that inhibits the histone acetyltransferase (HAT) activity of the transcription co-activators p300 and p300/CREB-binding protein-associated factor (pCAF; IC₅₀ values of 8.5 and 5 μM, respectively; Balasubramanyam et al.) Anacardic Acid inhibits HAT-dependent transcription and protein SUMOylation (Cui et al.; Fukuda et al.) In addition, Anacardic Acid is an activator of Aurora kinase A-mediated phosphorylation of Histone H3 (Kishore et al.) At higher concentrations (25 μM), Anacardic Acid suppresses NF-κB activation and inhibits IκB-α phosphorylation (Sung et al.)

Specifications

Description