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BMS 777607, MedChemExpress
MedChemExpress BMS 777607 (BMS 817378) is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3 with IC50s of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM, respectively, and 40-fold more selective for Met-related targets than Lck, VEGFR-2, and TrkA/B, with more than 500-fold greater selectivity versus all other receptor and non receptor kinases.
Brand: Medchem Express HY-12076

Description
BMS 777607 (BMS 817378) is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3 with IC50s of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM, respectively, and 40-fold more selective for Met-related targets than Lck, VEGFR-2, and TrkA/B, with more than 500-fold greater selectivity versus all other receptor and non receptor kinases.Specifications
BMS 777607 | |
White | |
C25H19ClF2N4O4 | |
BMS 817378 | |
O=C(NC1=CC=C(C(F)=C1)OC2=C(C(N)=NC=C2)Cl)C3=C(C=CN(C3=O)C4=CC=C(C=C4)F)OCC | |
512.89 | |
Research | |
Cancer-Kinase/protease |
1025720-94-8 | |
Research | |
100 mg | |
DMSO : ≥ 39 mg/mL (76.04 mM) | |
512.89 | |
98.49% | |
Solid |
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Research purposes only