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BMS 777607, MedChemExpress

MedChemExpress BMS 777607 (BMS 817378) is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3 with IC50s of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM, respectively, and 40-fold more selective for Met-related targets than Lck, VEGFR-2, and TrkA/B, with more than 500-fold greater selectivity versus all other receptor and non receptor kinases.

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1478.26 SEK - 13148.72 SEK

Specifications

Chemical Name or Material BMS 777607
CAS 1025720-94-8
Color White
Purity Grade Notes Research
Molecular Formula C25H19ClF2N4O4
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Description

Description

BMS 777607 (BMS 817378) is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3 with IC50s of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM, respectively, and 40-fold more selective for Met-related targets than Lck, VEGFR-2, and TrkA/B, with more than 500-fold greater selectivity versus all other receptor and non receptor kinases.
Specifications

Specifications

BMS 777607
White
C25H19ClF2N4O4
DMSO : ≥ 39 mg/mL (76.04 mM)
512.89
98.49%
Solid
1025720-94-8
Research
BMS 817378
O=C(NC1=CC=C(C(F)=C1)OC2=C(C(N)=NC=C2)Cl)C3=C(C=CN(C3=O)C4=CC=C(C=C4)F)OCC
512.89
Research
Cancer-Kinase/protease
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Safety and Handling

Safety and Handling

missing translation for 'shelfLife' : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month

Recommended Storage : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month

SDS
Documents

Documents

Product Certifications

Research purposes only

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