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Eurofins DiscoverX Pyk2 Protein, Active

Active, N-Terminal His6-tagged, recombinant, full-length, human Pyk2, for use in Kinase Assays.

Encompass_Preferred

6046.30 SEK - 46147.75 SEK

Specifications

Formulation mg/mL of enzyme in Tris/HCl pH 7.5, 150 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Molecular Weight (g/mol) 117.2 kDa
Species Human
Recombinant Recombinant
Protein Tag N-terminal 6His
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
17360354
Encompass_Preferred
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Eurofins DiscoverX
14-567 		10 μg
6046.30 SEK
10µg
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17370354
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Eurofins DiscoverX
14-567M 		250 μg
46147.75 SEK
250µg
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Description

Description

Proline-rich tyrosine kinase 2 (PTK2B) (also called CAKb for cell adhesion kinase b, RAFTK for related adhesion focal tyrosine kinase, or CADTK for calcium-dependent tyrosine kinase) is a non-receptor tyrosine kinase structurally related to focal adhesion kinase (FAK). PTK2B interacts with Src family kinases and focal adhesion proteins such as p130Crk-associated substrate (p130Cas) and its homologue p105 human enhancer of filamentation 1 (HEF1). PTK2B is particularly enriched in pulmonary vascular endothelial cells and lung, a major organ site for tumor metastasis. Inhibitors of PTK2B may be useful in the treatment of lung cancer.

GenBank S80542

Specifications

Specifications

mg/mL of enzyme in Tris/HCl pH 7.5, 150 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Human
N-terminal 6His
Full-length
Pyk2, active
117.2 kDa
Recombinant
Recombinant enzyme expressed in Sf21 insect cells
≥53%
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