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Lysing Tubes & Kits

Superior Efficiency for Difficult-to-lyse Sample Types

Get the best results from your sample preparation by using MP Biomedicals Lysing Matrix in combination with a FastPrep™ instrument.

With over 16 unique components, FastPrep™ Lysing Matrices are impact-resistant tubes containing specific beads to meet any of your lysing, grinding or homogenization needs. They are available in 2mL, 4.5mL, 15mL, 50mL, and 250mL sizes, as well as in 96 deep well plates.

Although they are designed to be used with a FastPrep™ homogenizer, the standard size of the tubes allows their use with many other bead beaters.

Ready-to-use Protocols for DNA and RNA Isolation From any Sample

MP Biomedicals supplies a complete range of organic, spin column, and magnetic bead based extraction kits for the isolation of high quality DNA and RNA. All kits included in the FastPrep™ product line contain optimized Lysing Matrix tubes for the sample homogenization step and reagents for further DNA, RNA or protein isolation. Yields and processing times are greatly enhanced through the use of FastPrep™ homogenizers. 

Automated Extraction

MP Biomedicals MPure-32™ aNAP System

The MPure-32™ aNAP System is a fully automatic platform for magnetic reagent assays. It can process up to 32 samples simultaneously within a short period of time (around 40 to 60 minutes) while still achieving scientific and diagnostic requirements within a safe operating procedure. Besides its capability to extract nucleic acids with high purity and yield, the MPure-32™ aNAP System can also be used for protein extraction or separation of cells. It is easy to use for pre-filled or self-filled reagent plates.

• Easy to use and highly flexible: Built-in protocols with the touch of a button customize your own protocols for any specific application
• Minimal contamination risk: Built-in UV light reduces the chance of cross-contamination 
• Accurate temperature control system: Two heating blocks ensure your assay will be run at the optimal temperature for maximum yield, speed, and results consistency 

Flexible Magnetic-Bead Based Kits Specially Developed for Automated DNA and RNA Purification

Magbeads FastDNA and FastRNA kits are using magnetic beads technology with high binding capacity and selectivity for DNA and RNA to isolate nucleic acids. They include Lysing Matrix tubes for a thorough and rapid grinding of the sample.

High-quality nucleic acids isolated with the MagBeads Kits are suitable for a broad range of applications including real-time PCR and next-generation sequencing

• High quality DNA and RNA: Intact, high yield, and free from inhibitors
• Flexible: Compatible with a wide range of automated nucleic acid purification platforms
• Versatile: Dedicated kits for any specific application

Cell Culture

Mycoplasma Removal

One of the major issues in dealing with mammalian cell culture is infection due to mycoplasma. The presence of mycoplasma can alter many cellular processes and cause malfunctioning of cells in proliferation, protein synthesis, DNA transfection, etc. MP Biomedicals™ offers a complete solution for mycoplasma contamination in cell culture, from prevention, rapid detection (20 min), and sensitive detection (10CFU/mL) to effective removal (fast and low cytotoxicity).

Successfully treat infected cell culture with MRA, the most reliable solution for mycoplasma removal and prevention, ensuring quality results, including:

• Fastest (1 week) with lowest dosage (0.5μg/mL)
• Elimination of multiple mycoplasma species
• Prevention of recontamination
• Sterility and optimal cell viability
• Compatible with mammalian cell lines
• Widely cited and highly recognized (550+ publications) 

7X™ - Cleaning Solutions

Trusted by labs worldwide and available exclusively from MP Biomedicals, 7X™ solutions have been used for over 50 years to provide safe and effective cleaning of laboratory benches and apparatus whenever a high degree of cleanliness is required. They are of particular value in cell culture laboratories where they have a number of advantages:

7X™ cleaning solutions should be of particular value in cell culture laboratories where

• Suitable for washing away DNase/RNase, bacteria, radioactive contaminants and sticky biologicals
• Suitable for manual washing & ultrasonic cleaning
• Suitable for automatic washers/sprayers
• Supplied as a convenient ready-to-use 5% solution

FastGro: Chemically Defined FBS Replacement

Fetal bovine serum (FBS) is widely used as a serum-supplement for in vitro cell culture media. FBS promotes healthy cell growth by providing an undefined mixture of nutrients, such as proteins, attachment factors, growth factors, lipids and hormones. However, due to its undefined nature, FBS can lead to unexpected and undesired stimulation of cells. There is also biorisk from animal protein or pathogen contamination, including risk of bovine spongiform encephalopathy (BSE). To avoid these concerns, MP Biomedicals™ has launched FastGro™, a fully chemically defined FBS replacement for cell culture use. It allows culturing of a wide range of cells in vitro without the use of serum or any animal or human derived compounds.

• Chemically defined nature without lot-to-lot variations 
• No animal or human derived materials or compounds 
• No interference with hormones or growth factors 
• Elimination of the risk of contaminants - viruses, mycoplasma, prions, etc
• Wide range of cell culture practices 
• Storage in the refrigerator – no need for thawing before use 

Encapsulated Media

The ultimate in consistency & accuracy, MP Biomedicals is well known for providing high-quality growth media in a variety of formulations for every molecular biologist. We specialize in formulations for yeast and bacteria and offer more than a thousand recipes and variations. MP Biomedicals is the only source of encapsulated growth media. Our patented media capsules eliminate the waste, inaccuracies, and mess associated with weighing out bulk powder. Each recipe is subjected to extensive quantitative testing, and is Molecular Biology Certified™ through qualitative tests such as cell density and plasmid yield. Easy to use. Simply drop the capsule in water and autoclave. No Mess. No Cleanup.

Biochemicals

Premium Dextran Sulfate Sodium Salt (DSS)

DSS is a polyanionic derivative of Dextran offered at the highest quality and purity, and in the most reproducible form. It is a potent intestinal inflammation reagent and the gold standard in colitis research.

DSS is a polyanionic derivative of Dextran offered at the highest quality and purity, and in reproducible form.

DSS is one of the most common and effective compounds used to trigger colitis in mice and rats when administered in drinking water. The DSS colitis model has also been used extensively to study colon cancer.

Because of its high efficacy, MP Biomedicals™ Premium DSS (MW = 36,000–50,000) is one of the most widely used DSS products in the scientific literature.

MP Biomedicals™ Premium DSS technical advantages:

• Induces severe colitis (inflamatory bowel disease)
• Highest sulfur content – 19%
• Highest chirality - +104° of specific rotation 
• Lowest pH – 6.2 at 1% solution